Pancreatic Cyst Fluid - Cytology

Message

Performed in the Cytology Laboratory x5839.
Must submit with Cytolgoy paper requisition #151594 available from Taylor Communications (Smartworks)

Test Code

PANC CYST CYTO

CPT Codes
88112

Includes

Routine evaluation to rule out malignancy. Also available is corresponding fluid CEA and Amylase testing via send out to Interpace Diagnostics in Pittsburgh, PA. See collection instructions below. Combined Cytology and Interpace report are used to determine further Molecular Testing (PancraGen). PancraGen tests for KRAS Point Mutation as well as loss of heterozygosity panels.

Preferred Specimen

If only Cytology is requested, cyst fluid can be dispensed into Cytolyt tube provided by the Cytology Laboratory. For CEA/Amylase +/- Molecular testing, obtain collection kit directly from Interpace Diagnostics prior to procedure.

Minimum Volume

Any volume can be evaluated for Cytology although higher volumes, if available, yield better results. CEA/Amylase +/- Molecular Testing requires at least 0.25cc.

Instructions

Collection for CEA and/or Amylase Testing WITH CYTOLOGY:

Obtain Interpace submission kit.
Control sample is obtained by using the “Cyto-Pak Cytosoft Brush” to swab the inside of the patient’s cheek (buccal swab).
Submit 0.25cc cyst fluid in clear 2ml tube(s) included in the kit.
Any additional fluid is then expressed out of the needle into the Cytolyt tube.
Interpace requisition completed by GI and demographic face sheet submitted.
Cytology Lab requisition #151594 is also completed.
Labels MUST be affixed to the buccal swab, 2ml tube(s) and the Cytolyt tube. Unlabeled tubes will be rejected.
All tubes and requisitions are packaged inside the bag and delivered immediately to Cytology Lab in Ziskind 530.

Transport Container

Cytoloyt tube for Cytology. Interpace Diagnostics kit for CEA/Amylase +/- Molecular.

Transport Temperature

Refrigerate if arrival in Cytology will exceed 10 minutes.

Methodology
Liquid based cytology slide preparation.

Setup Schedule

Daily, Monday through Friday

Report Available

Cytology, CEA, Amylase and Molecular results are provided together within the Cytology report.

Reference Range

CEA Result	Cytology Result
<5ng/ML - NO Molecualr	Negative - NO Molecular
5-192ng/mL Reflexive Molecular Testing	Atypical - Reflexive Molecular
> 192ng/mL - NO Molecular	Suspicious or Positive - NO Molecular

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.