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Valproic Acid
MessageSerum half-life is 8 - 12 hours
Performed in the Chemistry Laboratory, x5820
10.2018
Performed in the Chemistry Laboratory, x5820
10.2018
Test Code
VALP
Alias/See Also
Known also as Depakene or Depakote
CPT Codes
80164
Preferred Specimen
Plasma from a green top (PST) tube
Minimum Volume
1 mL
Instructions
Draw specimen at steady state reached approximately at 2 - 4 days.
Trough: Collect within an hour of the next dose. Sample preferably before the AM dose.
Check level if dosing changed or if additional anticonvulsants are given.
Centrifuge within 2 hours of collection
Trough: Collect within an hour of the next dose. Sample preferably before the AM dose.
Check level if dosing changed or if additional anticonvulsants are given.
Centrifuge within 2 hours of collection
Transport Container
Green Top (PST) tube
Transport Temperature
Room temperature
Specimen Stability
No Add-On
Methodology
Chemisluminescent Microparticle Immunoassay (Abbott Architect i2000)
Setup Schedule
This assay is performed 24 hours per day, 7 days per week
Reference Range
Therapeutic range: 50 - 100 ug/mL
Critical alert value: ≥ 150 ug/mL
Critical alert value: ≥ 150 ug/mL
Clinical Significance
Valproic acid is an anticonvulsant drug.
This test is used to monitor compliance, assess clinical effectiveness, or determine toxicity.
This test is used to monitor compliance, assess clinical effectiveness, or determine toxicity.
