Protein S Antigen, free

Message

Performed in the Hematology Laboratory x5475, 76. Sample MUST be drawn to minimum fill line on tube.

Test Code

PSAG

CPT Codes
85305

Preferred Specimen

plasma

Minimum Volume

2.7 mL. Sample MUST be drawn to minimum fill line on tube or the sample will be rejected as QNS.

Instructions

If drawn with other coagulation assays: for up to 3 tests draw 1, 2.7mL sodium citrate tubes. For 4 or more coagulation tests, draw 2, 2.7 mL sodium citrate tubes.

Transport Container

Light Blue Top (Sodium Citrate), 2.7 mL draw tubes

Transport Temperature

Room temperature

Specimen Stability

Refrigerator Stability: 4 hours
Plasma is stable for 6 months frozen at -70 degrees C.

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis, QNS, Clotted

Methodology

Turbidimetric Immunoassay

Setup Schedule

Performed 1x/week, weekdays between 8-4pm

Limitations

An increase in the C4b-Binding protein (an acute phase reactant) may result in a decreased free Protein S antigen.

Reference Range

0 -	5 days	22%	78%
		22%	78%
5 days -	1 month	33%	93%
		33%	93%
1 month -	3 months	54%	118%
		54%	118%
3 months -	6 months	55%	119%
		55%	119%
6 months -	150 years	60%	150%
		60%	150%
**Female Ranges are in BLUE

Clinical Significance

Performed when the Protein S activity is decreased to identify a qualitative or quantitative deficiency.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.