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Phenytoin (Dilantin)
MessageSerum half-life is 8 - 60 hours (does dependent)
Performed in the Chemistry Laboratory x5820.
10.2018
Performed in the Chemistry Laboratory x5820.
10.2018
Test Code
PHENYTOIN
Alias/See Also
Dilantin
CPT Codes
80185
Preferred Specimen
Plasma from a green top (PST) tube
Minimum Volume
1 mL
Instructions
IV infusion: at least 6 - 8 hours post loading dose
Chronic monitoring: any consistent sampling time
Check level at least 3 - 4 days after a change in dose
Chronic monitoring: any consistent sampling time
Check level at least 3 - 4 days after a change in dose
Transport Container
Green Top (PST) tube
Transport Temperature
Room temperature
Specimen Stability
No Add-On
Methodology
Chemisluminescent Microparticle Immunoassay (Abbott Architect i2000)
Setup Schedule
This assay is performed 24 hours per day, 7 days per week
Reference Range
Therapeutic range: 10 - 20 ug/mL
Critical alert value : ≥ 30 ug/mL
Critical alert value : ≥ 30 ug/mL
Clinical Significance
This test is used to monitor compliance, assess clinical effectiveness, or determine toxicity.
