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Methotrexate
MessagePerfromed in Chemistry Laboratory x5820
Please notifiy the lab that a specimen is coming when placing an order for methotrexate
09.2018
Please notifiy the lab that a specimen is coming when placing an order for methotrexate
09.2018
Test Code
MTX
CPT Codes
80299
Preferred Specimen
Serum from a plain red top tube
Minimum Volume
1 mL
Other Acceptable Specimens
Gold top (SST) tube
Instructions
Draw specimen at steady state reached at 24-48 hours.
Serum half-life for low dose: 3 - 10 hours
Serum half-life for high dose: 8 - 15 hours
Serum half-life for low dose: 3 - 10 hours
Serum half-life for high dose: 8 - 15 hours
Transport Container
Plain Red Top tube
Transport Temperature
Room Temperature
Specimen Stability
2 - 8 oC: 7 days
Methodology
Homogeneous Immunoassay
Setup Schedule
This assay is performed 24 hours per day, 7 days per week
Limitations
Not for patients who have received Glucarpidase within the past 5 - 7 days
Reference Range
Critical Value:
5.0 - 10 umol/L (24 hours)
0.5 - 1.0 umol/L (48 hours)
> 0.1 umol/L (72 hours)
5.0 - 10 umol/L (24 hours)
0.5 - 1.0 umol/L (48 hours)
> 0.1 umol/L (72 hours)
Clinical Significance
This test is used to monitor levels of Methotrexate to ensure appropriate therapy.
