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Hemoglobinopathy Screen
MessagePerformed by the Hematology Laboratory x5475, 75
Test Code
HGBSC
CPT Codes
82664
Includes
Hemoglobin identification by HPLC, quantitation of hemoglobins A2 and F.
Evaluation of RBC morphology. Citrate agar gel electrophoresis and/or
ZPP as needed for diagnostic interpretation by Hematology Pathologist.
Evaluation of RBC morphology. Citrate agar gel electrophoresis and/or
ZPP as needed for diagnostic interpretation by Hematology Pathologist.
Preferred Specimen
whole blood
Minimum Volume
1 mL
Instructions
Requires Pathologist sign-out.
Other Hematology tests requiring a Purple Top (EDTA) tube can
also be performed on this sample. If other tests are ordered,
a minimum of 3 mL is required.
Other Hematology tests requiring a Purple Top (EDTA) tube can
also be performed on this sample. If other tests are ordered,
a minimum of 3 mL is required.
Transport Container
3 mLPurple Top (EDTA)
Transport Temperature
Room Temperature
Specimen Stability
Refrigerated: 7days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis or QNS. Sample can be evaluated if clotted if
sufficient red cells can be salvaged for testing.
sufficient red cells can be salvaged for testing.
Methodology
HPLC and electrophoresis. Sent out for molecular testing if necessary.
Setup Schedule
Tuesday and Fridays, 9-3 pm
Reference Range
AA pattern is normal. Refer to other specific tests for reference ranges. Final interpretation by Pathologist.
Clinical Significance
Evaluation of anemia or the presence of abnormal hemoglobins for genetic counciling.
