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B2 Glycoprotein I Antibody, IgG and IgM Classification
MessagePerformed in the Hematology Laboratory x5475, 76.
Can combine with ACA (Anti Cardiolipin Antibody test)
Can combine with ACA (Anti Cardiolipin Antibody test)
Test Code
B2GAB
Alias/See Also
B2 GPI
CPT Codes
86146
Includes
B2 Glycoprotein I IgG and IgM quantitation
Preferred Specimen
Plasma
Minimum Volume
2.7 mL. Sample must be drawn to minimum fill line on tube or the sample will be rejected as QNS.
Instructions
Sample can also be used for ACA (Anticardiolipin Assay)
Transport Container
2.7 mL sodium citrate Blue Top tube
Transport Temperature
Room Temperature
Specimen Stability
Sample should be spun upon receipt. Plasma is stable:
Room temperature: 8 hours
Refrigerated at 2-8° C : 48 hours
Frozen at -70° C : 6 months
Room temperature: 8 hours
Refrigerated at 2-8° C : 48 hours
Frozen at -70° C : 6 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
QNS or Clotted
Methodology
ELISA technique is used to detect antibodies to B2 Glycoprotein I
Setup Schedule
1x / week, weekdays between 8-4 pm. Sample is frozen until testing is performed.
Limitations
When negative anti-b2GPI titers are found in the presence of clinical indications, lupus anticoagulant, anticardiolipin, or other additional testing is indicated. Diagnosis can not be made on the basis of anti-B2GPI testing alone; results must be interpreted in conjunction with physical findings.
Reference Range
IgG: 0-20 SGU
IgM: 0-20 SMU
Clinical Significance
Marker for thrombotic risk, used in conjunction with ACA (Anti Cardiolipin Antibodies)
