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Anti-Xa Assay
MessagePerformed in the Hematology Laboratory, x5475, 76.
Sample MUST be drawn to minimum fill line on tube.
This assay is used to monitor UFH (unfractionated heparin) and LMWH (Low Molecular Weight Heparin)
Sample MUST be drawn to minimum fill line on tube.
This assay is used to monitor UFH (unfractionated heparin) and LMWH (Low Molecular Weight Heparin)
Test Code
XA
Alias/See Also
Anti Xa Assay
CPT Codes
85520
Preferred Specimen
plasma
Minimum Volume
2.7 mL. Sample MUST be drawn to minimum fill line on tube or the sample will be rejected as QNS.
Instructions
Deliver to lab immediately. If the assay is for LMWH, specify which LMWH the patient is receiving. Must collect 4 hours after last dose of LMWH.
Transport Container
Light Blue Top (Sodium Citrate), 2.7 mL draw tubes
Transport Temperature
Room Temperature
Specimen Stability
Sample Stability: 1 hour for UFH/LMWH monitoring
Stable for 6 months frozen at -70 degrees C.
Stable for 6 months frozen at -70 degrees C.
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, QNS, clotted
Methodology
Chromogenic assay
Setup Schedule
As requested, 24/7
Limitations
No interference up to 300 mg/dL of hemoglobin, 800 mg/dL of triglycerides, and 20 mg/dL of bilirubin.
Reference Range
Therapeutic range for LMWH is 0.5-1.0 IU/mL
Therapeutic range for UFH is 0.3 - 0.7 IU/mL
Therapeutic range for UFH is 0.3 - 0.7 IU/mL
Clinical Significance
To monitor heparin therapy (low molecular weight and unfractionated)

