Idylla Cancer Mutation Test

Message
Performed in Cytogenetics/Molecular Genetic Laboratory (617-636-5841)


Test Code
NRAS


Alias/See Also
NRAS gene panel analysis
Biocartis Idylla


CPT Codes
81311, 81210

Preferred Specimen
FFPE tissue (curl) from unstained tissue, solid tumors only
H&E slide


Minimum Volume
tumor cell content >= 10% neoplastic cells
tissue curl size >= 50mm2 x 5 um or 25 mm2 x 10 um


Instructions
Testing ordered by TMC case pathologist. FFPE curl and H&E slide will be made inhouse by Histology Lab unless provided.
H&E slide required to assess tumor cell content.


Transport Container
RNAse free micro nunc tubes


Transport Temperature
2 - 25 degrees Celsius


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
  • Insufficient amount of curl material
  • Insufficient tumor cell content
  • Curl obtained from stained tissue
  • Curl cut > 60 days prior to testing


Setup Schedule
Curls will be processed Monday-Friday during normal business hours.


Clinical Significance
Gene panel analysis is designed to identify actionable mutations for colorectal cancer, lung cancer, and melanoma, among other solid tumor types.




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.