Reticulocyte Hemoglobin

Message

Performed in the Hematology Laboratory x5475, 76
Performed along with a CBC

Test Code

RetHe

CPT Codes
85046

Preferred Specimen

whole blood

Minimum Volume

0.5 mL

Instructions

Performed with CBC
Other Hematology tests requiring a Purple Top (EDTA) tube can
also be performed on this sample. If other tests are ordered,
a minimum of 3 mL is required

Transport Container

3 mL Purple top (EDTA)

Transport Temperature

Room Temperature

Specimen Stability

Stable for 6 hurs at Room Temperature, or up to 24 hours at 2-8ᵒ C

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Grossly hemolyzed, QNS, clotted

Methodology
Flow cytometric staining and light scatter

Setup Schedule

24/7

Reference Range

RetHe: 28.7 - 35.7 pg

Clinical Significance

RetHe is a measurement of the hemoglobin content of reticulocytes and reflects the functional
availability of iron. RetHe is useful in the diagnosis and management of iron deficiency anemia.
RetHe below normal (<28.7 pg) indicates an early iron deficiency state. RetHe is not affected
by inflammatory conditions and therefore it aids diagnosis of iron deficiency in the setting of
chronic disease. RetHe is used to monitor response to iron substitution and erythropoietin
treatment and is particularly recommended for evaluation of chronic renal disease (CKD)
related anemia.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.