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Factor VIII Activity
(Chromogenic assay)

Message
This test is not orderable outside of LIS (SOFT).
Intended for monitoring Factor VIII Levels in the
extended half-life (EHL) Factor VIII Replacement
products only.


Test Code
F8CH


Alias/See Also
Chromogenic Factor VIII Assay


CPT Codes
85240

Preferred Specimen
Plasma


Minimum Volume
2.7 mL. Sample MUST be drawn to minimum fill line on tube or the sample will be rejected as QNS.


Instructions
If drawn with other coagulation assays: for up to 3 tests draw 2, 2.7 mL sodium citrate tubes. For 4 or more tests, draw 3, 2.7 mL sodium citrate tubes.


Transport Container
Light Blue Top (Sodium Citrate), 2.7 mL draw tubes


Transport Temperature
Room Temperature


Specimen Stability
Refrigerator Stability: 4 hours
Plasma is stable for 6 months frozen at -70 degrees C.


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross Hemolysis, QNS, Clotted


Methodology
Chromogenic Assay

Setup Schedule
Batched as needed


Reference Range
0  - 5 days 50% 154%
    50% 154%
5 days  -  1 month 50% 157%
    50% 157%
1 month  - 3 months 50% 125%
    50% 125%
3 months-   6 months 50% 109%
    50% 109%
6 months - 150 years 50% 150%
    50% 150%
**Female Ranges are in BLUE  


Clinical Significance
Perferred Methodology for monitoring FVIII Levels in the new extended
half-life (EHL) FVIII replacement products (i.e. Adynovate)




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.