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iFOBT test for Colorectal Neoplasm
MessagePerformed in the Hematology Laboratory x5475,76.
Performed on Outpatients only. Not available for in-house use.
Patients may be sent home to collect sample.
Performed on Outpatients only. Not available for in-house use.
Patients may be sent home to collect sample.
Test Code
OBCRN
Alias/See Also
Colorectal Cancer screen
CPT Codes
82274
Preferred Specimen
OC-Auto Micro 80 sampling bottle inoculated with a fecal sample
Transport Temperature
Room temperature
Specimen Stability
Samples are stable for 15 days at room temperature, 30 days if stored at 2-8°C.
Methodology
The OC-Auto Micro 80 Fecal Occult Blood test is an immunological assay that determines the presence of human hemoglobin in a fecal sample. Latex reagent, prepared by sensitizing anti-human HbA0 antibodies to polystyrene latex particles is mixed with sample. The antibodies react with hemoglobin in the sample, resulting in a latex agglutination reaction. The reaction is analyzed for changes in optical density, with the amount of change increasing in proportion to higher concentrations of hemoglobin.
Setup Schedule
Tuesday and Friday, after 5 pm.
Limitations
No dietary restrictions or medication interferences
Reference Range
Negative
Clinical Significance
This test is intended for the qualititative detection of fecal occult blood (human hemoglobin). The test is useful for the determination of gastrointestinal bleeding, found in a number of GI disorders, e.g. colrectal cancer, colitis, and polyps. This test does not offer conclusive evidence of a GI pathology; it is only intended for preliminary screening.
