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Factor XIII Antigen
MessagePerformed in the Hematology Laboratory x5475, 76.
Sample MUST be drawn to minimum fill line on tube
Sample MUST be drawn to minimum fill line on tube
Test Code
F13AG
Preferred Specimen
plasma
Minimum Volume
2.7 mL sodium citrate tubes. Sample MUST be drawn to minimum fill line on tube or the sample will be rejected as QNS.
Instructions
If drawn with other coagulation assays: For up to 3 tests draw 2, 2.7 mL sodium citrate tubes. For 4 or more coagulation tests, draw 3, 2.7 mL sodium citrate tubes.
Transport Container
Light blue top (sodium citrate), 2.7 mL draw tube.
Transport Temperature
Room Temperature
Specimen Stability
Refrigerator Stability: 4 hours
Plasma is stable for 6 months frozen at -70 degrees C.
Plasma is stable for 6 months frozen at -70 degrees C.
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly hemolyzed, QNS, clotted.
Methodology
Turbidimetric Immunoassay
Setup Schedule
As needed.
Limitations
Results are not affected by hemoglobin up to 500 mg/dL, bilirubin up to 18 mg/dL, triglycerides up to 1280 mg/dL, and rheumatoid factor up to 500 IU/mL.
Reference Range
| 0 - | 5 days | 44% | 144% |
| 44% | 144% | ||
| 5 days - | 1 month | 39% | 147% |
| 39% | 147% | ||
| 1 month - | 3 months | 36% | 172% |
| 36% | 172% | ||
| 3 months - | 6 months | 46% | 162% |
| 46% | 162% | ||
| 6 months - | 150 years | 75% | 150% |
| 75% | 150% | ||
| **Female Ranges are in BLUE | |||
Clinical Significance
FXIII is essential for maintaining hemostasis due to its role in fibrin stabilization and in the protection of fibrin from proteolytic degradation. This assay helps to detect any FXIII deficiencies in a bleeding patient.
