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Tacrolimus (LC-MS/MS)
MessagePerformed in the Metabolic Laboratory (x6-7919) On weekends and holidays, testing will be performed in the Chemistry Laboratory by an immunoassay method. See test code TACRI.
Half-life is 12 hours.
Half-life is 12 hours.
Test Code
TACRO
Alias/See Also
FK506
CPT Codes
80197
Preferred Specimen
Purple top (EDTA). Whole blood only. Tube cannot be used if plasma has been removed.
Minimum Volume
0.5 mL
Other Acceptable Specimens
None
Instructions
Therapeutic monitoring: TROUGH: collect within an hour of next dose.
Transport Temperature
Room temperature
Methodology
LC-MS/MS
FDA Status
Not FDA approved. Lab developed test.
Setup Schedule
Specimens must be in the lab by 10:30 AM for same day results Mon-Fri. Specimens must be in the lab by 9:30 AM for same day results on weekends and hospital holidays.
Reference Range
Trough: 3-20 ng/mL. Therapeutic goal depends on type of transplant and time since transplant. Note: The immunoassay method (see test code TACRI) produces measurements that are approximately 10-15% higher than LC-MS/MS.
