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Troponin I
Test CodeTNIA
CPT Codes
84484
Preferred Specimen
1.0 mL plasma/1.0 mL serum
Transport Container
Green Top Tube/Gold Top tube
Transport Temperature
Refrigerated
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed specimen
Methodology
Electrochemiluminescence Immunoassay
Reference Range
<0.30 ng/mL
Clinical Significance
Troponin is a protein complex which regulates the contraction of striated muscle. In acute coronary syndromes (ACS), it can be detected in blood at 4-8 hours following the onset of chest pain, has a peak concentration at 12-16 hours, and remains elevated for 5-9 days. ACS represents a continuum of increasing risk from asymptomatic coronary artery disease to myocardial ischemia and thrombus development. Patients with a very low troponin have a good short term prognosis. Troponin I has been used as a reliable marker in the diagnosis of perioperative myocardial infarction in patients undergoing cardiac surgery.