Alkaline Phosphatase, Serum

Test Code

ALKP

CPT Codes
84075

Preferred Specimen

1.0 mL serum

Transport Container

Gold top tube

Transport Temperature

Room Temperature or Refrigerate.

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis

Methodology
Colorimetric

Reference Range

	Male	Female
6 days-6mon	<449 U/l	<449 U/L
7 mon-1 year	<462 U/L	<462 U/L
1-3 years	<281 U/L	<281 U/L
4-6 years	<269 U/L	<269 U/L
7-12 years	<300 U/L	<300 U/L
13-17 years	<390 U/L	<187 U/L
>18 Years	40-130 U/L	35-105 U/L

Clinical Significance

Alkaline phosphatase in serum consists of four structual genotypes: the liver-bone-kidney type, the intestinal type, the placental type and the variant germ cells. It occurs in osteoblasts, hepatocytes, leukocytes, the kidneys, spleen, placenta, prostate and the small intestine. The liver-bone-kidney type is particularly important. A rise in alkaline phosphatase occurs with all forms of cholestasis, particularly with obstructive jaundice. It also elevated in diseases of skeletal system, sucha as Paget's disease, hyperthyroidism, rickets and osteomalacia, as well as with fractures and malignant tumors.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.