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Rheumatoid Factor Quantitation

Test Code
RA


Alias/See Also
RF


CPT Codes
86430

Preferred Specimen
SERUM


Transport Container
Serum Seprator Tube (SST)


Transport Temperature


Refrigerated




Specimen Stability
Room Temperature18–28 °C (64–82 °F)    ≤ 1 day
Refrigerated 2–8 °C (36–46 °F)          ≤ 3 days
Frozen ≤-20 °C (≤-4 °F)                      ≤ 6 months


Methodology
Immunoturbidimetric

Setup Schedule
Tuesday and Friday


Reference Range
<12 IU/ML


Clinical Significance
Rheumatoid factor (RF) consists of autoantibodies of immunoglobulin isotypes IgM, IgA, IgG, and IgE.1 The function of RFremains unclear, but it may play a role in the regulation of humoral and cellular immunity and protection against invadingmicroorganisms.2 Most patients with rheumatoid arthritis and Sjögren’s syndrome have elevated levels of RF. RF may alsobe elevated in scleroderma, dermatomyositis, Waldenström’s disease, sarcoidosis, and systemic lupus erythematosus.3 Thereare also instances of elevated RF without apparent disease or definable clinical disorders.



Last Updated: July 13, 2018


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.