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Hepatitis A (IgM), Acute Status
Test Code512
Preferred Specimen
1 mL serum (0.5 mL minimum)
Transport Container
SST
Transport Temperature
Room temperature, stable 14 days
Methodology
Immunoassay
Reference Range
Nonreactive
Clinical Significance
IgM antibodies against Hepatitis A Virus (HAV) are detected soon after onset of symptoms. Persistence of the IgM response is extremely variable, with specific IgM detected for less than one month in some cases and greater than one year in others. In most cases, IgM antibodies against HAV persist for a period of three to six months after which they decline to levels that are below detection. Anti-HAV IgM detection can be useful for the differential diagnosis of hepatitis A from other forms of viral hepatitis.
Last Updated: September 3, 2010