Rickettsia (RMSF) Antibodies (IgG, IgM) with Reflex to Titers

Message

If the RMSF IgG screen is detected, then the RMSF IgG Titer, TC900330, will be performed at an additional charge (CPT: 86757). If the RMSF IgM screen is detected, then the RMSF IgM Titer, TC900327, will be performed at an additional charge (CPT: 86757).

SRHC Clients:

1 gold top tube or 1 red top tube
Gross hemolysis or gross lipemia are acceptable
Transport to SRHC laboratory within 8 hours

Test Code

LAB1264

Quest Code

6419

Alias/See Also

Rocky Mountain Spotted Fever IgG, IgM w/Reflex titer
RMSF IgG & IgM, IFA

CPT Codes
86757 (x2)

Includes

If RMSF IgG is Detected, then RMSF IgG Titer will be performed at an additional charge (CPT code(s): 86757).
If RMSF IgM is Detected, then RMSF IgM Titer will be performed at an additional charge (CPT code(s): 86757).

Preferred Specimen

1 mL serum

Minimum Volume

0.2 mL

Transport Container

Plastic screw-cap vial

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic

Methodology
Immunofluorescence Assay (IFA)

Setup Schedule

Set up: Tues-Sat; Report available: 1-4 days

Limitations

Even after infection has been treated, positive results may persist. False-positive reactions may occur during pregnancy.

Reference Range

	Screen	Titer
RMSF (IgG)	Not detected	<1:64
RMSF (IgM)	Not detected	<1:64

Clinical Significance

Antigen specific IgG and IgM titers allow rapid diagnosis of infection by any of the spotted fever group of rickettsial agents. This group of agents include R. rickettsii (Rocky Mountain Spotted Fever) and R. akari (rickettsial pox), both seen in the continental United States.

Performing Laboratory

Quest Diagnostics Nichols Institute

14225 Newbrook Drive

Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.