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| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Cytomegalovirus Antibody (IgM)
MessageSRHC Clients:
- 1 gold top tube or 1 red top tube
- Transport to SRHC laboratory within 8 hours
Test Code
LAB957
Quest Code
8503
Alias/See Also
CMV IgM AB
CPT Codes
86645
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly hemolyzed or lipemic samples
are unacceptable.
are unacceptable.
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues, Thurs, Sat a.m.; Report available: Next day
Limitations
False-positive IgM test results may be due to the presence of heterophile antibodies or presence of rheumatoid factor.
Reference Range
< 0.90: Negative
___ < 0.90: Negative, no CMV IgM Antibody detected
_ 0.90-1.10: Equivocal
> or = 1.11: Positive, CMV IgM Antibody detected
Results from any one IgM assay should not be used as a
sole determinant of a current or recent infection.
Because an IgM test can yield false positive results and
low levels of IgM antibody may persist for more than 12
months post infection, reliance on a single test result
could be misleading. If an acute infection is suspected,
consider obtaining a new specimen and submit for both IgG
and IgM testing in two or more weeks.
___ < 0.90: Negative, no CMV IgM Antibody detected
_ 0.90-1.10: Equivocal
> or = 1.11: Positive, CMV IgM Antibody detected
Results from any one IgM assay should not be used as a
sole determinant of a current or recent infection.
Because an IgM test can yield false positive results and
low levels of IgM antibody may persist for more than 12
months post infection, reliance on a single test result
could be misleading. If an acute infection is suspected,
consider obtaining a new specimen and submit for both IgG
and IgM testing in two or more weeks.
Clinical Significance
CMV infections are common and usually asymptomatic. In patients who are immunocompromised, CMV may cause disseminated, severe disease. CMV may cause birth defects in a minority of infected newborns.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153
