Hepatitis B Surface Antigen with Reflex Confirmation

Message

Positive samples will be confirmed based on the manufacturer's FDA approved recommendations at an additional charge (CPT code(s): 87341).
Note: When only a single test, Hepatitis B Surface Antigen, is ordered to diagnose Hepatitis B in a pregnant woman, additional tests such as liver enzymes should be ordered to confirm the diagnosis.

SRHC Clients:

1 gold top tube or 1 red top tube
Transport to SRHC laboratory within 8 hours

Test Code

LAB44725

Quest Code

498

Alias/See Also

Hepatitis B Surface Antigen, Qualitative
HBsAG

CPT Codes
87340

Includes

Positive samples will be confirmed based on the manufacturer's FDA approved recommendations at an additional charge (CPT code(s): 87341).

Preferred Specimen

2 mL serum (1 mL minimum)

Minimum Volume

1 mL

Other Acceptable Specimens

Plasma collected in: EDTA (lavender-top) tube

Instructions

Note: When only a single test, Hepatitis B Surface Antigen, is ordered to diagnose Hepatitis B in a pregnant woman, additional tests such as liver enzymes should be ordered to confirm the diagnosis.

Transport Temperature

Refrigerated, stable 14 days

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis or gross lipemia

Methodology
Immunoassay (IA)

Setup Schedule

Set up: Mon-Sat; Report available: Next day

Limitations

Results obtained from immunosuppressed patients should be interpreted with caution. Patients receiving mouse antibody therapy may produce false-negative results

Reference Range

Non-Reactive

Clinical Significance

Surface antigen usually appears in the serum after an incubation period of 1 to 6 months following exposure to Hepatitis B virus and peaks shortly after onset of symptoms. It typically disappears within 1 to 3 months. Persistence of Hepatitis B Surface Antigen for greater than 6 months is a prognostic indicator of chronic Hepatitis B infection.

Performing Laboratory

Quest Diagnostics Nichols Institute

14225 Newbrook Drive

Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.