A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Cryptococcal Antigen, Latex Screen with Reflex to Titer

Message
If Cryptococcal antigen screen result is detected, equivocal, or indeterminate, then a reflex to titer will be performed at an additional charge (CPT: 86406).

SRHC Clients:

Cerebrospinal fluid:  Order CCAF (CSF Cryptococcal Antigen)
  • 1 mL CSF in sterile screw-cap container
  • Transport to lab as soon as possible


Serum: Order CCA  (Cryptococcal Antigen on Serum)
 

  • 2 mL serum from gold top tube or red top tube
  • Transport to lab as soon as possible


                    
                                      

 

 



Test Code
LAB927


Quest Code
11196


Alias/See Also


Cryptococcal Antigen Latex on CSF or Serum




CPT Codes
86403

Includes
If Cryptococcal Antigen Screen is Detected, then Cryptococcal Antigen, Latex Titer will be performed at an additional charge (CPT code(s): 86406).


Preferred Specimen
1 mL CSF collected in a sterile, leakproof container or 2 mL serum collected in a serum separator tube (SST)


Minimum Volume
0.5 mL


Instructions
Centrifuge serum specimens within 1 hour of collection. Transfer serum to clean, plastic, screw-capped vial(s). Refrigerate samples and transport on refrigerant coolant, or, freeze samples and transport on dry ice to the laboratory.


Transport Container
CSF: Sterile screw-cap vial
Serum: Plastic screw-cap vial


Transport Temperature


Frozen:  -70C




Specimen Stability
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 60 days


Methodology
Latex Agglutination (LA)

Setup Schedule
Set up: Daily p.m. (eveninng, night shift); Report available: Next day


Limitations
Patients with capnocytophaga canimorsus and tichosporon beigelli infections may test falsely-positive.


Reference Range
Not detected


Clinical Significance
The encapsulated soil yeast Cryptococcus neoformans causes Cryptococcosis. Pulmonary infection is acquired by inhalation of the organism and is usually subclinical in the immunocompetent host. Dissemination may occur in an immunocompromised patient, often to the meninges.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153




The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.