Diphtheria and Tetanus Antitoxoids

Test Code

DIPTA

Quest Code

34042

Alias/See Also

DIPHTHERIA/TETANUS

CPT Codes
86648, 86774

Preferred Specimen

2 mL serum collected in each of two separate tubes

Minimum Volume

0.3 mL (x2)

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Grossly icteric

Methodology
Immunoassay (IA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Daily; Report available: 1-4 days

Reference Range

Diphtheria Antitoxoid	≥0.10 IU/mL
Tetanus Antitoxoid	≥0.10 IU/mL

Clinical Significance

Used to evaluate diphtheria immunization response. Antibody levels of ≥0.10 IU/mL are considered protective.

Tetanus is caused by Clostridium tetani. Immunization with Tetanus Antitoxoid is effective with boosters in immunocompetent individuals. Antibody levels of ≥0.10 IU/mL are considered protective. However, tetanus can still occur in some individuals with such antibody levels. These results should not be used to determine the necessity to administer antitoxin when clinically indicated.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Dr
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.