Susceptibility, Antimicrobial, AFB, Rapid Grower, MIC

Test Code

MICRGQ

Quest Code

19079

Alias/See Also

ANTIMICROB,AFB,MIC

CPT Codes
87186

Includes

Amikacin, Cefoxitin, Ciprofloxacin, Clarithromycin, Clofazimine, Doxycycline, Imipenem, Linezolid, Moxifloxacin, Tigecycline, Tobramycin, Trimethoprim/Sulfamethoxazole

Preferred Specimen

Pure culture of a Runyon group IV mycobacteria (Rapid Growers), submitted in appropriate culture media on a plate or slant, safely contained

Minimum Volume

1 slant/plate/broth

Instructions

Identification of the isolate is required.

Isolate safely contained in a double-walled safety container or must be submitted in 95K bag at room temperature. Lowenstein-Jensen or Middlebrook 7H10 agar slant/plate or equivalent or positive AFB broth medium (requires subculture prior to testing) or any solid microbiological medium that supports growth.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: Determined by viability
Refrigerated: Determined by viability
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Mixed cultures or organisms not considered rapid growing mycobacteria • Raw specimens • Frozen isolates • Isolates overgrown with bacteria, yeast, fungi

Methodology
Broth Microdilution

FDA Status
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.

Setup Schedule

Set up: Mon, Tues, Fri a.m.; Report available: 14-21 days

Reference Range

See Laboratory Report

Clinical Significance

The role of rapidly growing Mycobacteria, especially M. fortuitum and M. chelonae, as agents of human disease has become more clearly established in modern times. Primary antitubercular drugs generally are not effective in the treatment of these organisms. Therapy had shifted to the use of antimicrobial agents routinely used to treat other bacterial infections.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.