Comprehensive Metabolic Panel with Fibrosis-4 (FIB-4) Index

Test Code

10372

CPT Codes
80053, 85049

Includes

Comprehensive Metabolic Panel: Albumin, Albumin/Globulin Ratio (calculated), Alkaline Phosphatase, ALT, AST, BUN/Creatinine Ratio (calculated), Calcium, Carbon Dioxide, Chloride, Creatinine with GFR Estimated, Globulin (calculated), Glucose, Potassium, Sodium, Total Bilirubin, Total Protein, Urea Nitrogen
Platelet Count
FIB 4 Index

Preferred Specimen

1 mL serum collected in a serum separator tube (SST) and one full tube whole blood collected in an EDTA (lavender-top) tube

Patient Preparation
Fasting specimen is preferred

Minimum Volume

0.5 mL serum • 1 mL EDTA whole blood or 0.5 mL microtainer-lavender

Instructions

Whole blood: Maintain specimen at room temperature. Do not refrigerate. If multiple draw, collect lavender-top tube last. Traumatic venipuncture tap can introduce thromboplastin and trap white blood cells and platelets. Refrigeration can precipitate fibrin and trap white blood cells and platelets.

Transport Container

Serum separator tube (SST) and EDTA (lavender-top) tube

Transport Temperature

Room temperature

Specimen Stability

Serum
Room temperature: 72 hours
Refrigerated: 72 hours
Frozen: Unacceptable

Whole blood
Room temperature: 48 hours

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

See individual tests

Methodology
Electronic Cell Sizing/Counting/Cytometry/Microscopy • Spectrophotometry (SP)

Reference Range

See Laboratory Report

Clinical Significance

The FIB-4 index is a simple non-invasive approach using selected laboratory measures (AST, ALT, platelet count) in combination with patient age to assess if an individual is at higher risk for advanced liver fibrosis (F3-F4).

Performing Laboratory

Quest Diagnostics-Seattle

1737 Airport Way S Suite 200

Seattle, WA 98134-1636

Last Updated: November 6, 2024

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.