C4d Fragment, EIA

Test Code

4943

CPT Codes
83520

Preferred Specimen

1 mL plasma collected in an EDTA (lavender-top) tube

Minimum Volume

0.2 mL

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 4 hours
Frozen: 14 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis • Received room temperature • Received refrigerated

Methodology
Enzyme Immunoassay (EIA)

FDA Status
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.

Setup Schedule

Tues

Report Available

3-10 days

Reference Range

0.9-8.0 mcg/mL

Clinical Significance

Clinical use is to exclude known rheumatoid arthritis, systemic lupus erythematosus, and chronic uticaria with hypocomplementemia. C4d is a stable activation product of C4 cleavage, and is useful to determine classical pathway complement activation.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

Last Updated: November 6, 2024

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.