Chemzyme Plus

Test Code

7964

Includes

Chemzyme, HDL Cholesterol, LDL Cholesterol, Cholesterol/HDL Cholesterol Ratio

Preferred Specimen

Refer to individual tests

Patient Preparation
If a cholesterol measurement is to be performed along with triglycerides, but not part of a lipid panel, then the patient should be fasting 9-12 hours prior to collection.
If the cholesterol is ordered as part of a lipid panel, then a fasting sample is not required.

The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been...determined to interfere with assays for...cholesterol, uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.

Instructions

Note: N-acetyl-p-benzoquinone imine (NAPQI) (metabolite of acetaminophen) will generate erroneously low results in samples for patients that have taken toxic doses of acetaminophen.

Specimen Stability

See individual tests

Reference Range

See Laboratory Report

Last Updated: November 6, 2024

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.