Chromosome Analysis, POC Tissue

14593

This germline genetic test requires physician attestation that patient consent has been received if ordering medical facility is located in AK, DE, FL, GA, IA, MA, MN, NV, NJ, NY, OR, SD or VT or test is performed in MA.

5x5 mm tissue collected in a sterile container in Hanks', Ringer's solution, or culture medium with antibiotics

2x3 mm

Tissue in saline solution • Cultured cells collected in flasks

Fetal tissue sample minimum of 2x3 mm collected in a sterile container with Hank's, Ringer's solution, culture medium with antibiotics, or saline solution.

Transport media should be refrigerated before use, but can be shipped at room temperature.

Sterile screw-cap container

Room temperature

Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.

Daily

15 days

See Laboratory Report

Chromosome analysis of products of conception (POC) can detect fetal chromosome abnormalities, which are associated with approximately one-half of all first trimester spontaneous abortions. Chromosome testing on fibroblasts obtained from a tissue biopsy is performed to investigate tissue specific mosaicism not present in blood lymphocytes. Fresh cells from tissue biopsies obtained postmortem may still be suitable for chromosome analysis when the patient's blood is not available or viable. If chromosome analysis is unsuccessful, please contact the laboratory genetic counselor at 1-866-GENEINFO (1-866-436-3463) to discuss the option of adding chromosomal microarray (CMA) testing.