Cholinesterase, Serum, Plasma, RBC (CA Clients)

Test Code

90369

CPT Codes
82480 (x2), 82482

Preferred Specimen

5 mL uncentrifuged whole blood collected in an EDTA (lavender-top) tube and
1 mL plasma collected in an EDTA (lavender-top) tube and
1 mL serum

Minimum Volume

4 mL whole blood • 0.5 mL plasma • 0.5 mL serum

Other Acceptable Specimens

Plasma collected in: PPT potassium EDTA (white-top) tube

Instructions

Transfer plasma and serum to transport tubes and send refrigerated with whole blood.

Note: PPT potassium EDTA (white-top) tubes should be centrifuged within 24 hours

Transport Container

EDTA (lavender-top) tube and transport tube(s)

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 24 hours
Refrigerated: 7 days
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis • Lipemia • Received room temperature • Received frozen

Methodology
Kinetic Spectrophotometric (KS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

This test code is California patient testing. For non-California testing, use test code 39481.

Setup Schedule

Tues-sat

Report Available

2-5 days

Reference Range

See Laboratory Report

Clinical Significance

True cholinesterase (RBC and plasma) activity is decreased in individuals with exposure to organophosphorous insecticides. True cholinesterase, found in erythrocytes and nerve tissue, is responsible for inactivating acetylcholinesterase at nerve endings. With decreased enzyme activity, patients may display a range of nervous system dysfunction. Analysis of RBC and serum or plasma activity is useful in monitoring exposure and recovery.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

Last Updated: November 6, 2024

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.