C-Peptide Stimulation by Glucagon

Test Code

14747

CPT Codes
84681 (x4)

Includes

Baseline, 5 minutes, 10 minutes, 15 minutes

Preferred Specimen

2 mL frozen serum for each timed specimen

Patient Preparation
Overnight fasting is required

Minimum Volume

0.4 mL for each timed specimen

Instructions

Draw baseline fasting specimen. Administer 1 mg Glucagon by I.V. Draw additional samples at 5,10 and 15 minutes. Collect 2 mL serum for each timed specimen. All tubes must be clearly marked with time drawn. Submit all tubes with one test requisition.
Note: Glucagon is not supplied by Quest Diagnostics.

Transport Container

Transport tube (x4)

Transport Temperature

Frozen

Specimen Stability

Room temperature: 24 hours
Refrigerated: 7 days
Frozen -20° C: 28 days
Frozen -70° C: 12 months

Methodology
Immunochemiluminometric Assay (ICMA)

Reference Range

Baseline	0.80-3.10 ng/mL
5 minutes	Not available
10 minutes	Not available
15 minutes	See Laboratory Report

Clinical Significance

C-Peptide Stimulation by Glucagon is useful in assessing patients for pancreatic beta cell function and reserve. Patients with Type I diabetes mellitus have decreasing reserves of beta cell function.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

Last Updated: November 6, 2024

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.