Cyclosporine A, Blood

Test Code

4845

CPT Codes
80158

Preferred Specimen

4 mL EDTA whole blood
Note: Each test sample(s) must be bagged separately from other accessions

Minimum Volume

1 mL

Transport Temperature

Refrigerated preferred
Room temperature acceptable

Methodology
High Performance Liquid Chromatography (HPLC)

Setup Schedule

Mon-Fri: Rcvd by 11 a.m., out by 4:30 p.m.; Sat, Sun, holiday: Rcvd by 10 a.m., out by 4:30 p.m. Daily

Report Available

2 days

Reference Range

No definitive therapeutic or toxic ranges have been established. The following trough level ranges are suggested guidelines

Kidney Transplantation	100-200 µg/L
Other Organ Transplant	200-300 µg/L

Clinical Significance

Cyclosporine (Cyclosporine A) is an immunosuppressant therapeutic agent used in the prevention of organ graft rejection. Clinical measurement of blood levels is required due to the inter-individual variability of metabolism as well as the toxicity associated with excessive dosage. Measurement of whole blood levels has been recommended because of the slow temperature dependent equilibration of cyclosporine between plasma and red blood cells.

Performing Laboratory
University of Washington Medical Center
1959 NE Pacific St, Lab Med Box 357110
Seattle, WA 98195-0001

Last Updated: November 6, 2024

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.