| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Creatinine Clearance without Glomerular Filtration Rate, Estimated (eGFR)
Test Code19118
CPT Codes
82575
Includes
Creatinine (serum and urine), Creatinine Clearance (calculation)
Preferred Specimen
10 mL aliquot from a well-mixed 24-hour urine collection - no preservative
and 1 mL serum
and 1 mL serum
Minimum Volume
0.5 mL urine • 0.5 serum
Instructions
Record total volume and collection time on specimen container and requisition. Indicate the patient's height and weight on the test requisition.
Note: A serum creatinine level must be collected within 24 hours of the beginning or ending of the urine collection.
Note: A serum creatinine level must be collected within 24 hours of the beginning or ending of the urine collection.
Transport Container
Urine: Plastic urine container
Serum: Transport tube
Serum: Transport tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Grossly icteric
Methodology
Spectrophotometry (SP)
Reference Range
Serum Creatinine
Creatinine, 24-Hour Urine
Urine Creatinine Clearance
| Age | Male (mg/dL) | Female (mg/dL) |
| ≤2 days | 0.79-1.58 | 0.79-1.58 |
| 3-27 days | 0.35-1.23 | 0.35-1.23 |
| 1 month-9 years | 0.20-0.73 | 0.20-0.73 |
| 10-12 years | 0.30-0.78 | 0.30-0.78 |
| 13-15 years | 0.40-1.05 | 0.40-1.00 |
| 16-17 years | 0.60-1.20 | 0.50-1.00 |
| 18-29 years | 0.60-1.24 | 0.50-0.96 |
| 30-39 years | 0.60-1.26 | 0.50-0.97 |
| 40-49 years | 0.60-1.29 | 0.50-0.99 |
| 50-59 years | 0.70-1.30 | 0.50-1.03 |
| 60-69 years | 0.70-1.35 | 0.50-1.05 |
| 70-79 years | 0.70-1.28 | 0.60-1.00 |
| ≥80 years | 0.70-1.22 | 0.60-0.95 |
Creatinine, 24-Hour Urine
| <3 Years | Not established |
| 3-8 Years | 0.10-0.80 g/24 h |
| 9-12 Years | 0.20-1.40 g/24 h |
| 13-17 Years | 0.40-1.90 g/24 h |
| >17 Years | 0.50-2.15 g/24 h |
Urine Creatinine Clearance
| Male | 85-125 mL/minute |
| Female | 75-115 mL/minute |
Clinical Significance
Creatinine Clearance is used to evaluate the glomerular filtration rate (GFR). Clearance is defined as that volume of plasma from which a measured amount of substance could be completely eliminated into the urine per unit of time. Daily creatinine production is fairly constant except when there is massive injury to muscle.
Last Updated: November 6, 2024
