CDX2, IHC with Interpretation

Test Code

90153

CPT Codes
88342

Preferred Specimen

Formalin-fixed paraffin embedded tissue

Minimum Volume

IHC specimen transport kit

Other Acceptable Specimens

Unstained charged (+) slides collected in IHC specimen transport kit (x5)

Instructions

Please include surgical pathology report

Transport Container

IHC specimen transport kit

Transport Temperature

Room temperature

Specimen Stability

Room temperature: Indefinite
Refrigerated: Indefinite
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received frozen

Methodology
Immunohistochemistry

Setup Schedule

Mon-Fri

Reference Range

See Laboratory Report

Clinical Significance

CDX-2, a nuclear transcription factor that is expressed in colonic epithelium, is useful in distinguishing metastatic carcinoma of colorectal origin from other tumors. However, its expression may be lost in advanced colorectal tumors and is also expressed by some mucinous tumors of other sites.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

Last Updated: November 6, 2024

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.