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Lamotrigine Level
Test CodeLAMO
Alias/See Also
Lamictal Level
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Instructions
Draw specimen immediately before next scheduled dose or at least 12 hours after last dose.
Transport Container
Plastic vial
Transport Temperature
Ambient temperature
Specimen Stability
14 days ambient temperature
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis, gross lipemia, gross icterus
Report Available
2-4 days
Reference Range
Patients receiving therapeutic doses usually have lamotrigine concentrations of 2.5-15.0 mcg/mL.
Clinical Significance
Lamotrigine (Lamictal) is approved for therapy of bipolar I disorder and a wide variety of seizure disorders including Lennox-Gastaut syndrome, primary generalized tonic-clonic seizures, and partial seizures. Its many off-label uses include treatment of migraine, trigeminal neuralgia, and treatment-refractory depression.
Performed By
Quest Diagnostics DEMO
Last Updated: April 14, 2017
