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Histone Autoantibodies
Test CodeAHIST
Preferred Specimen
1 mL serum
Minimum Volume
0.4 mL
Transport Container
Plastic vial
Transport Temperature
Refrigerated
Specimen Stability
21 days refrigerated
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross lipemia, Gross hemolysis
Report Available
3-6 days
Reference Range
See report for normal ranges.
Clinical Significance
Histone antibody is present in 80-95% of patients with drug-induced Systemic Lupus Erythematosus (SLE), 20-50% of patients with idiopathic SLE, and infrequently in patients with other autoimmune connective tissue diseases.
Performed By
Quest Diagnostics DEMO
Last Updated: April 14, 2017