Rheumatoid Arthritis Diagnostic Panel

Test Code

17669

CPT Codes
86200, 86431

Includes

Rheumatoid Factor
Cyclic Citrullinated Peptide (CCP) Antibody (IgG)

Preferred Specimen

2 mL serum

Minimum Volume

1 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Plasma

Methodology
Immunoturbidimetry • Immunoassay (IA)

Setup Schedule

Set up: Mon-Fri; Report available: 1-4 days

Reference Range

Rheumatoid Factor	<14 IU/mL
CCP Antibody, IgG
Negative	<20
Weak Positive	20-39
Moderate/Strong Positive	40-59
Strong Positive	>59

Clinical Significance

The combination of RF and anti-CCP antibodies provide greater specificity for the diagnosis of Rheumatoid Arthritis (RA). CCP antibodies may be present earlier than RF and often indicate increased erosive disease in RA.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

Last Updated: May 19, 2016

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.