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Chlamydia/Neisseria gonorrhoeae RNA, TMA with Reflex to Alternate Target, Urogenital
Test Code91773
CPT Codes
87494
Includes
Chlamydia trachomatis RNA, TMA, Urogenital
Neisseria gonorrhoeae RNA, TMA, Urogenital
If Chlamydia trachomatis RNA, TMA, Urogenital is Detected, then Chlamydia trachomatis, TMA (Alternate Target), Urogenital will be performed at an additional charge (CPT code(s): 87491).
If Neisseria gonorrhoeae RNA, TMA, Urogenital is Detected, then Neisseria gonorrhoeae, TMA (Alternate Target), Urogenital will be performed at an additional charge (CPT code(s): 87591).
If both C. trachomatis RNA, TMA, Urogenital and N. gonorrhoeae RNA, TMA, Urogenital are detected, TMA (Alternate Target) will be performed at an additional charge (CPT code(s): 87494).
Preferred Specimen
1 vaginal, endocervical or urethral swab in Aptima® Transport Tube or
2 mL urine in Aptima Transport Tube or
1 mL liquid cytology (PreservCyt®) Preservative (ThinPrep®) in Aptima® Transfer Tube or
0.5 mL SurePath™ Preservative Fluid in Aptima® Transfer Tube
2 mL urine in Aptima Transport Tube or
1 mL liquid cytology (PreservCyt®) Preservative (ThinPrep®) in Aptima® Transfer Tube or
0.5 mL SurePath™ Preservative Fluid in Aptima® Transfer Tube
Patient Preparation
Urine: Patient should not have urinated within one hour prior to collection. Female patients should not cleanse the labial area prior to providing the specimen.
Minimum Volume
1 vaginal, endocervical or urethral swab in Aptima® Transport
2 mL urine collected in an Aptima® Transport tube
1 mL liquid cytology (PreservCyt®) preservative (ThinPrep®) in Aptima® Transfer tube
0.5 mL SurePath™ fluid submitted in an Aptima® Transfer tube
2 mL urine collected in an Aptima® Transport tube
1 mL liquid cytology (PreservCyt®) preservative (ThinPrep®) in Aptima® Transfer tube
0.5 mL SurePath™ fluid submitted in an Aptima® Transfer tube
Instructions
Vaginal swab: Follow instructions in the Aptima® Multitest Collection Kit (orange label).
Endocervical or Urethral swab: Follow instructions in the Aptima® Unisex Swab Specimen Collection Kit (white label). In females, to ensure collection of cells infected with N. gonorrhoeae/C. trachomatis, columnar epithelial cells lining the endocervix should be obtained. Excess mucus should be removed prior to sampling.
Urine: Direct patient to provide a first-catch urine (a maximum of 20-30 mL of the initial urine stream) into a urine collection cup free of any preservatives. 2 mL of urine specimen must be transferred into the Aptima® Specimen Transport Tube within 24 hours of collection and before being assayed. Use the tube provided in the urine specimen collection kit. The fluid (urine plus transport media) level in the urine transport tube must fall within the clear pane of the tube label.
Labs performing cytology: Aliquot ThinPrep® PreservCyt®solution before performance of liquid-based cytology testing. ThinPrep® PreservCyt®: Transfer 1 mL ThinPrep® PreservCyt® solution into Aptima® Specimen Transfer Tube (green label) or Aptima® Multitest Collection Tube (orange label) or Unisex Swab Specimen Collection Tube (white label).
SurePath™: SurePath™ fluid must be transferred to Aptima® tube within 4 days of collection. Transfer 0.5 mL SurePath™ solution into Aptima® Specimen Transfer Tube (green label) or Aptima® Multitest Collection Tube (orange label) or Unisex Swab Specimen Collection Tube (white label). Urine: Patient should not have urinated within one hour prior to collection. Female patients should not cleanse the labial area prior to providing the specimen.
Endocervical or Urethral swab: Follow instructions in the Aptima® Unisex Swab Specimen Collection Kit (white label). In females, to ensure collection of cells infected with N. gonorrhoeae/C. trachomatis, columnar epithelial cells lining the endocervix should be obtained. Excess mucus should be removed prior to sampling.
Urine: Direct patient to provide a first-catch urine (a maximum of 20-30 mL of the initial urine stream) into a urine collection cup free of any preservatives. 2 mL of urine specimen must be transferred into the Aptima® Specimen Transport Tube within 24 hours of collection and before being assayed. Use the tube provided in the urine specimen collection kit. The fluid (urine plus transport media) level in the urine transport tube must fall within the clear pane of the tube label.
Labs performing cytology: Aliquot ThinPrep® PreservCyt®solution before performance of liquid-based cytology testing. ThinPrep® PreservCyt®: Transfer 1 mL ThinPrep® PreservCyt® solution into Aptima® Specimen Transfer Tube (green label) or Aptima® Multitest Collection Tube (orange label) or Unisex Swab Specimen Collection Tube (white label).
SurePath™: SurePath™ fluid must be transferred to Aptima® tube within 4 days of collection. Transfer 0.5 mL SurePath™ solution into Aptima® Specimen Transfer Tube (green label) or Aptima® Multitest Collection Tube (orange label) or Unisex Swab Specimen Collection Tube (white label). Urine: Patient should not have urinated within one hour prior to collection. Female patients should not cleanse the labial area prior to providing the specimen.
Transport Temperature
Room temperature
Specimen Stability
Liquid cytology (Preservcyt® Preservative (ThinPrep®)
Room temperature: 14 days
Refrigerated: 30 days
Frozen: 1 year
SurePath™ Preservative Fluid
Room temperature: 14 days
Refrigerated: 14 days
Frozen: Unacceptable
Urine in Aptima® Transport Medium
Room temperature: 30 days
Refrigerated: 30 days
Frozen: 1 year
Swabs in Aptima® Transport
Room temperature: 60 days
Refrigerated: 60 days
Frozen: 1 year
Room temperature: 14 days
Refrigerated: 30 days
Frozen: 1 year
SurePath™ Preservative Fluid
Room temperature: 14 days
Refrigerated: 14 days
Frozen: Unacceptable
Urine in Aptima® Transport Medium
Room temperature: 30 days
Refrigerated: 30 days
Frozen: 1 year
Swabs in Aptima® Transport
Room temperature: 60 days
Refrigerated: 60 days
Frozen: 1 year
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Transport tubes with 2 swabs • Transport tubes with Non-APTIMA® swabs • Specimens in broken containers • Swab transport tubes with no swab • Swab submitted in viral transport media; Urine samples where the fluid level is not between the black fill lines • PreservCyt® ThinPrep® material previously processed for cytology • PreservCyt® ThinPrep® with excess mucus
Methodology
Transcription-Mediated Amplification (TMA)
Setup Schedule
Set up: Daily; Report available: 1-2 days
Clinical Significance
To screen for the infection with Neisseria gonorrhoeae and Chlamydia trachomatis in vaginal, endocervical and urethral swabs or urine from men and women.
Performing Laboratory
| Quest Diagnostics Nichols Institute |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |
Last Updated: November 6, 2024
