Coccidioides Antibodies (IgG, IgM), Immunodiffusion

Test Code

19963

CPT Codes
86635 (x2)

Includes

Antibody to TP Antigen (IgM) and Antibody to F Antigen (IgG)

Preferred Specimen

0.5 mL serum

Minimum Volume

0.1 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic • Grossly icteric

Methodology
Immunodiffusion (ID)

Setup Schedule

Set up: Mon, Wed, Fri, Sat; Report available: 3-6 days

Reference Range

Ab to TP Antigen (IgM), ID	Negative
Ab to F Antigen (IgG), ID	Negative

Clinical Significance

Detection of antibodies to Coccidioides antigens plays an important role in identifying patients with coccidioidomycosis. Antibodies to Coccidioides TP antigen usually appear during the first week of infection, and remain detectable for approximately 5 months; their detection indicates recent, active infection. Antibodies to Coccidioides F antigen appear within a month of infection, and remain detectable for up to a year thereafter.

Performing Laboratory

Quest Diagnostics Nichols Institute

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

Last Updated: November 6, 2024

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.