Meningitis/Encephalitis Panel, PCR, CSF

Test Code
38799


CPT Codes
87483

Includes
Escherichia coli K1, Haemophilus influenzae, Listeria monocytogenes, Neisseria meningitidis (encapsulated), Streptococcus agalactiae, Streptococcus pneumoniae, Cytomegalovirus, Enterovirus, Herpes Simplex Virus 1, Herpes Simplex Virus 2, Human Herpesvirus 6, Human parechovirus, Varicella Zoster Virus, Cryptococcus neoformans/gattii


Preferred Specimen
1 mL CSF collected in a sterile, plastic, screw-cap container


Minimum Volume
0.3 mL


Instructions
Collection CSF specimens should be collected via lumbar puncture and should not be centrifuged. This test is not intended for use with CSF collected from indwelling medical devices (e.g. CSF Shunts).


Transport Temperature
Refrigerated (cold packs)


Specimen Stability
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: Unacceptable


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
CSF Collected from indwelling medical devices (e.g. CSF Shunts)


Methodology
Polymerase Chain Reaction

Setup Schedule
Set up: Daily; Report available: 2 days


Reference Range
See Laboratory Report


Clinical Significance
The Meningitis/Encephalitis (ME) Panel is an FDA approved qualitative multiplex nucleic acid-based test that detects and identifies bacterial, viral and yeast DNA/RNA directly from a single aliquot of cerebrospinal fluid (CSF) in about one hour. ME panel is an aid for the diagnosis of specific agents of meningitis and/or encephalitis and results are meant to be used in conjunction with other clinical, epidemiological, and laboratory data including standard of care, culture for organism recovery, serotyping, and antimicrobial susceptibility testing. The results are not intended to be used as the sole basis for diagnosis, treatment, or other patient management decisions. The following organisms are identified: Bacteria: Escherichia coli K1, Haemophilus influenzae, Listeria monocytogenes, Neisseria meningitidis (encapsulated), Streptococcus agalactiae, Streptococcus pneumoniae Viruses: Cytomegalovirus, Enterovirus, Herpes Simplex Virus 1, Herpes Simplex Virus 2, Human Herpesvirus 6, Human parechovirus, Varicella Zoster Virus. Yeast: Cryptococcus neoformans/gattii


Performing Laboratory
med fusion
2501 South State Hwy 121, Suite 1100
Lewisville, TX 75067-8188



Last Updated: November 6, 2024


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.