Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Assay, Spinal Fluid

Test Code

94036

Alias/See Also

1230120107 | LAB100782: NMO/AQP4-IgG, FACS, CSF, Reflex to Titer | QUEST EAP: 94036 | NMO|AQ4

CPT Codes
86053

Includes

When the results of this assay require further evaluation, NMOTC / Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Fluorescence-Activated Cell Sorting (FACS) Titer Assay, Spinal Fluid will be performed at an additional charge.

Preferred Specimen

3 mL CSF collected in a sterile, leak-proof container

Minimum Volume

2 mL

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 72 hours
Refrigerated: 28 days
Frozen: 28 days

Methodology
Flow Cytometry

FDA Status
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

Setup Schedule

Set up: Mon, Tues, Thurs; Report available: 5-8 days

Reference Range

Negative

Clinical Significance

Diagnosis of a neuromyelitis optica spectrum disorder (NMOSD). Diagnosis of autoimmune AQP4 channelopathy. Distinguishing NMOSD from multiple sclerosis early in the course of disease.

Performing Laboratory
Mayo Clinic Laboratories
200 First Street SW
Rochester, MN 55905

Last Updated: April 21, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.