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Coccidioides Antibody, Complement Fixation, Serum

Test Code
906


Alias/See Also
1230101092 | LAB791: Coccidioides Antibodies by CF | QUEST EAP: 906 | ANTIBODY|SAN JOAQUIN FEVER|VALLEY FEVER


CPT Codes
86317

Preferred Specimen
1 mL serum


Minimum Volume
0.2 mL


Instructions
For CSF, use test code 5295X Coccidioides Antibody, Complement Fixation, CSF.


Transport Temperature
Room temperature


Specimen Stability
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric


Methodology
Complement Fixation (CF)

Setup Schedule
Set up: Mon, Wed, Fri, Sat; Report available: 3-6 days


Limitations
False-negatives may occur in patients with solitary pulmonary lesions. Patients with active histoplasmosis may generate cross reactions. Elevated serum antibodies may be present in patients with meningeal coccidiocomycosis.


Reference Range
<1:2 titer

Interpretive Criteria
<1:2Antibody Not Detected
≥1:2Antibody Detected


Clinical Significance
Infection by Coccidioides immitis can produce a spectrum of disease, with most patients being asymptomatic and some developing disseminated disease, including pneumonia and meningitis.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153


Last Updated: April 21, 2023


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.