Histoplasma Antibody, Immunodiffusion

Test Code

526

Alias/See Also

1230000241 | LAB200228: Histoplasma Ab by ID | QUEST EAP: 526

CPT Codes
86698

Includes

M Band and H Band

Preferred Specimen

1 mL serum

Minimum Volume

0.2 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly icteric • Grossly lipemic

Methodology
Immunodiffusion (ID)

Setup Schedule

Set up: Mon, Wed, Fri, Sat; Report available: 3-6 days

Reference Range

M Band	Negative
H Band	Negative

Clinical Significance

This immunodiffusion assay is highly specific for histoplasmosis infection but may have low sensitivity in early infection. Two different immunoprecipitin bands may be detected. The M band develops with acute infection, is often present in chronic infection, and may persist for months to years. The H band, which is usually present with the M band, generally suggests a chronic or severe acute infection. The presence of both the H and M bands is considered conclusive for the diagnosis of histoplasmosis.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

Last Updated: April 21, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.