Hexosaminidase A and Total Hexosaminidase, Leukocytes

Test Code

34842

Alias/See Also

1230400865 | LAB9009: Hexosaminidase A and Total, WBC | QUEST EAP: 34842 | TAY SACH DISEASE CARRIER (FEMALE)

CPT Codes
83080 (x2)

Preferred Specimen

6 mL whole blood collected in an ACD (yellow-top) tube

Minimum Volume

5 mL

Instructions

New York state clients: Informed Consent is required. Please document on the request form or electronic order that a copy is on file.

Specimen must arrive at Mayo within 96 hours of draw to be stabilized. Draw specimen Monday through Thursday only and not the day before a holiday. Specimen should be drawn and packaged as close to shipping time as possible

Draw blood in ACD solution A or B (yellow-top) tube(s) and send 6 mL of ACD whole blood (refrigerated).
(Keep specimen cool with frozen coolant April-October. Protect specimen from freezing by placing it in a bubble-pack supplied by Mayo Medical Laboratories, use refrigerated coolant November-March).

Specimen cannot be frozen. Do not transfer blood to other containers.

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 4 days
Refrigerated: 4 days
Frozen: Unacceptable

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis

Methodology
Fluorometric • Heat Inactivation • Semi-automated

Setup Schedule

Set up: Tues, Thurs; Report available: 4-8 days

Reference Range

Hexosaminidase Total
≤15 years	≥20 nmol/min/mL
≥16 years	16.4-36.2 nmol/min/mL
Hexosaminidase Percent A
≤15 years	20-80%
≥16 years	63-75%

Performing Laboratory
Mayo Clinic Laboratories
200 First Street SW
Rochester, MN 55905

Last Updated: April 21, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.