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Cytomegalovirus DNA, Quantitative Real-Time PCR, Plasma
Test Code10600
Alias/See Also
1231101088 | LAB913: CMV DNA Quant PCR | QUEST EAP: 10600X | CYTOMEGALOVIRUS
CPT Codes
87497
Preferred Specimen
2 mL plasma collected in an EDTA (lavender-top) tube
Minimum Volume
1 mL
Instructions
Do not freeze whole blood or samples stored in primary tube. Freshly drawn specimens (whole blood) may be stored at 2-25° C for up to 24 hours prior to centrifugation. Separate plasma from cells within 24 hours of collection by centrifugation. Follow manufacturer's instructions for collection tube handling.
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 6 days
Frozen -20° C: 84 days
Frozen -70° C: 6 months
Refrigerated: 6 days
Frozen -20° C: 84 days
Frozen -70° C: 6 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Sodium heparin (green-top) tube • Lithium heparin (green-top) tube • Unspun PPT tubes • Frozen whole blood
Methodology
Real-Time Polymerase Chain Reaction
Setup Schedule
Set up: Daily; Report available: 2-3 days
Reference Range
CMV DNA, QN PCR | Not Detected (IU/mL) |
CMV DNA, QN PCR | Not Detected (Log IU/mL) |
Clinical Significance
In patients who are immunocompromised, CMV may cause disseminated, severe disease. CMV is also the most common cause of congenital viral infection in humans. Quantitative PCR methods may be useful in monitoring CMV replication in immunosuppressed patients. This is a quantitative molecular test, with a linear range of 34.5-10,000,000 IU/mL (1.54-7.00 log IU/mL).
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Dr
Chantilly, VA 20153
Last Updated: April 21, 2023