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Chloride, Random Urine with Creatinine
Test Code1645
Preferred Specimen
10 mL random urine, no preservative in a plastic leak-proof container
Minimum Volume
2 mL
Other Acceptable Specimens
Urinalysis transport tube (yellow-top, blue fill line, preservative tube)
Instructions
Refrigerate during collection. Record total volume and collection duration on specimen container and test requisition.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Methodology
Ion Selective Electrode (ISE)
Setup Schedule
Set up: Daily; Report available: 2 days
Clinical Significance
Urine chloride excretion approximates the dietary intake. The chloride content of most foods parallel that of sodium. An increase in urine chloride may result from water deficient dehydration, diabetic acidosis, Addison's Disease, and salt-losing renal disease. Decreased urine levels are seen in congestive heart failure, severe diaphoresis and in hypochloremic metabolic alkalosis due to prolonged vomiting.
