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TRAcP, IHC with Interpretation
Test Code40020X
Preferred Specimen
Formalin fixed paraffin embedded tissue in an IHC specimen transport kit
Instructions
Pathology report is required
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Indefinite
Refrigerated: Indefinite
Frozen: Unacceptable
Refrigerated: Indefinite
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Tissue in formalin
Methodology
Immunohistochemical Stain
Setup Schedule
A.M. Sets up 5 days a week.
Clinical Significance
The histochemical identification of hairy cell leukemia via tartrate-resistant acid phosphatase assay has been a standard for over two decades. Anti-TRAcP antibody labels the cells of hairy cell leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osterclasts, which also express abundant TRAcP activity.