| A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Chromosome Analysis, POC Tissue with Reflex to Microarray, ClariSure® Oligo-SNP
Test Code91126
Includes
If Chromosome Analysis result is "Tissue has no growth", then Chromosomal Microarray, POC, ClariSure® Oligo-SNP will be performed at an additional charge (CPT code(s): 81229).
Preferred Specimen
5x5 mm tissue collected in a sterile container in Hanks', Ringer's solution or culture medium with antibiotics
Minimum Volume
2x3 mm
Other Acceptable Specimens
Tissue in saline solution • Cultured cells collected in flasks
Instructions
Fetal tissue sample minimum of 2x3 mm collected in a sterile container with Hanks', Ringer's solution, culture medium with antibiotics, or saline solution.
Transport media should be refrigerated before use, but can be shipped at room temperature.
Transport media should be refrigerated before use, but can be shipped at room temperature.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Preferred
Refrigerated: Acceptable
Frozen: Unacceptable
Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Refrigerated: Acceptable
Frozen: Unacceptable
Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Methodology
Culture • Karyotype • Microscopy
Setup Schedule
Chromosome reports 14 days/Micro-array 10 days if needed
Clinical Significance
Chromosome analysis of products of conception (POC) can detect fetal chromosome abnormalities that are associated with approximately one-half of all first trimester spontaneous abortions. Since chromosome analysis on products of conception has an increased failure rate, this test will reflex to chromosomal microarray if chromosome analysis fails. Chromosomal microarray (CMA) detects aneuploidies, deletions and duplications below the resolution of chromosome analysis (karyotyping), and long continuous regions of homozygosity.
