Fondaparinux Sodium (Xa Inhibition)

Test Code

16103

Preferred Specimen

1 mL citrated plasma collected in a 3.2% sodium citrate (light blue-top) tube

Minimum Volume

0.5 mL

Instructions

Collect 1 mL citrated plasma from a light blue-top tube (3.2% citrate), place in a sterile, plastic screw-capped vial, freeze and ship frozen

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 21 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolysis

Methodology
Anti-Xa Chromogenic

Setup Schedule

Set up: Mon-Fri; Report Available: 2-5 days

Clinical Significance

Fondaparinux sodium (Arixtra) is a factor Xa inhibitor indicated for the prophylaxis and treatment of deep venous thrombosis and pulmonary embolism in certain patient populations. The antithrombotic activity of Arixtra is the result of antithrombin III-mediated selective inhibition of Factor Xa. Neutralization of factor Xa interrupts thrombin formation and thrombus development. The anti-Factor Xa activity of the drug can be measured using the chromogenic anti-Xa method using Arixtra as the calibrator.

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.