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Procainamide (743X)
Test Code851N
Includes
Procainamide, N-acetylprocainamide, and Procainamide, Total
Preferred Specimen
1 mL serum collected in a red-top tube (red-top)
Patient Preparation
Collect as a trough just prior to next dose
Minimum Volume
0.2 mL
Other Acceptable Specimens
Plasma collected in: Sodium heparin (green-top) tube • Lithium heparin (green-top) tube • EDTA (lavender-top) tube
Instructions
Do not use gel barrier tubes
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: Not Established
Refrigerated: 7 days
Frozen: Not Established
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum Separator Tube (SST®)
Methodology
Immunoassay (IA)
Setup Schedule
Sets up 7 days a week.
Clinical Significance
Procainamide is used to treat a variety of atrial and ventricular arrhythmias. Metabolism of procainamide produces an active metabolite N-Acetylprocainamide (NAPA). The concentration of both procainamide and NAPA levels are monitored to assure adequate therapeutic levels of procainamide are achieved and to avoid toxicity.
