RPR (Monitor) with Reflex to Titer

Test Code

799

Includes

If RPR Screen is reactive, then RPR titer will be performed at an additional charge (CPT code(s): 86593).

Preferred Specimen

1 mL serum

Minimum Volume

0.6 mL

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Gross hemolysis • Grossly lipemic

Methodology
Flocculation

Setup Schedule

Set up: Mon, Wed-Sat; Report available: 1-3 days

Limitations

False-positive results have been associated in patients with infections, pregnancy, autoimmune disease, old age, Gaucher disease, and malignancy.

Clinical Significance

This is a nontreponemal (lipoidal antigen) serologic test used to monitor patients diagnosed with syphilis. RPR reactive samples will be reflexed to titer. Titer results may correlate with disease activity and typically decrease in response to treatment.

Serologic evaluation is recommended at 6 to 12 months for primary and secondary syphilis. Follow-up testing should be performed using the same nontreponemal (lipoidal antigen) test and be performed by the same laboratory so that results are comparable over time.

True positive results with nontreponemal (lipoidal antigen) tests may occur due to wide range of biological conditions (e.g., autoimmune disease, cancer, infectious diseases, old age, and pregnancy).

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.